BDBM404590 (3aR,6aR)-5- cyano-N-(4-(2- methylpyridin-4- yl)phenyl)hexa- hydropyrrolo[3,4- b]pyrrole-1(2H)- carboxamide::US10343992, Example 242::US10689345, Example 242::US11066365, Example 242::US11390584, Example 242
SMILES Cc1cc(ccn1)-c1ccc(NC(=O)N2CC[C@@H]3CN(C[C@H]23)C#N)cc1
InChI Key InChIKey=SVUMILBXHLHUDA-MJGOQNOKSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 404590
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:USP30 biochemical fluorescence intensity IC50 assay Dilution plates were prepared at 21 times the final concentration (2100 μM for a final conce...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:USP30 Biochemical Fluorescence Intensity Kinetic Assay.Reactions were performed in duplicate in black 384 well plates (small volume, Greiner 784076) ...More data for this Ligand-Target Pair