BDBM404592 (3aR,6aR)-5- cyano-N-(2'- methyl-[3,4'- bipyridin]-6- yl)hexahydro- pyrrolo[3,4-b] pyrrole-1(2H)- carboxamide::US10343992, Example 244::US10689345, Example 244::US11066365, Example 244::US11390584, Example 244
SMILES Cc1cc(ccn1)-c1ccc(NC(=O)N2CC[C@@H]3CN(C[C@H]23)C#N)nc1
InChI Key InChIKey=CYVRCSJGFVTEQR-SJORKVTESA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 404592
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:USP30 biochemical fluorescence intensity IC50 assay Dilution plates were prepared at 21 times the final concentration (2100 μM for a final conce...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:USP30 Biochemical Fluorescence Intensity Kinetic Assay.Reactions were performed in duplicate in black 384 well plates (small volume, Greiner 784076) ...More data for this Ligand-Target Pair