BDBM405268 1-(4-(7-(2,6-difluorobenzyl)-3-((dimethylamino)methyl)-5-(2-fluoro-3-methoxyphenyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-2-yl)phenyl)-3-methylurea::US10344034, Example 14::US10344034, Example 5::US10633388, Example 5
SMILES CNC(=O)Nc1ccc(cc1)-n1nc2n(Cc3c(F)cccc3F)c(=O)n(-c3cccc(OC)c3F)c(=O)c2c1CN(C)C
InChI Key InChIKey=LWHSAECBQVXZCR-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 405268
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical
US Patent
Shanghai Hengrui Pharmaceutical
US Patent
Affinity DataIC50: 0.660nMAssay Description:Human: Test Example 1. Human GnRHr (GnRH Receptor) Activity Assay of the Present Compounds.In vitro GnRHr protein activity was tested by the followin...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical
US Patent
Shanghai Hengrui Pharmaceutical
US Patent
Affinity DataIC50: 0.660nMAssay Description:In vitro GnRHr protein activity was tested by the following methods.This assay was used to determine the inhibition effect of the present compound on...More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical
US Patent
Shanghai Hengrui Pharmaceutical
US Patent
Affinity DataIC50: 0.110nMAssay Description:Human: Test Example 1. Human GnRHr (GnRH Receptor) Activity Assay of the Present Compounds.In vitro GnRHr protein activity was tested by the followin...More data for this Ligand-Target Pair