BDBM406108 (S)-4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(trifluoromethyl)phenyl)quinoline-7-carbonitrile::US10351563, Example 89::US10544120, Example 89::US10981910, Example 89

SMILES CC(C)C[C@@](C)(COc1ccc(cc1C(F)(F)F)-c1ccnc2cc(ccc12)C#N)NC(=O)OC(C)(C)C

InChI Key InChIKey=KYPPABUFZUNHDQ-NDEPHWFRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 406108   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406108((S)-4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(trif...)
Affinity DataIC50:  0.660nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406108((S)-4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(trif...)
Affinity DataIC50:  0.660nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM406108((S)-4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(trif...)
Affinity DataIC50:  0.660nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent