BDBM406663 US10336752, Compound 1::US10336752, Compound 2::US10336752, Compound 4::US10336752, Compound 5::US10336752, Compound 6::US11040967, Compound 6

SMILES Fc1cccc(F)c1-c1cc(Nc2ccc(cc2)C(=O)N2CCCC2)c2C(=O)NCc2n1

InChI Key InChIKey=XEOSMOXXYGCQLD-UHFFFAOYSA-N

Data  1 KI  24 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 406663   

TargetJAK3/JAK1(Homo sapiens (Human))
Nimbus Therapeutics

Curated by ChEMBL
LigandPNGBDBM406663(US10336752, Compound 1 | US10336752, Compound 2 | ...)
Affinity DataIC50:  240nMAssay Description:Inhibition of Jak1/Jak3 in human PBMC assessed as inhibition of IL2-stimulated phosphorylation of STAT5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed