BDBM407436 (R)-4-((3-cyano- bicyclo[1.1.1]pentan-1- yl)amino)-6-(3-cyano- pyrrolo[1,2-b]pyridazin- 7-yl)-N-(2-fluoro-3- hydroxy-3-methylbutyl) nicotinamide::US10336762, Compound 378
SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1NC12CC(C1)(C2)C#N)-c1ccc2cc(cnn12)C#N
InChI Key InChIKey=KJKGUZFQEALOBK-BURHJUHKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 407436
Affinity DataIC50: <1nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair