BDBM407451 (R)-6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-4-((4-(3- (difluoromethyl)azetidine-1- carbonyl)bicyclo[2.2.2] octan-1-yl)amino)-N-(2- fluoro-3-hydroxy-3- methylbutyl)nicotinamide::US10336762, Compound 393
SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1NC12CCC(CC1)(CC2)C(=O)N1CC(C1)C(F)F)-c1ccc2cc(cnn12)C#N
InChI Key InChIKey=TUVGTCGGVHQDEL-WQWRHJRMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 407451
Affinity DataIC50: <1nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair
Affinity DataEC50: 44nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair