BDBM407464 (R)-6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-4-((4- (cyclopropylcarbamoyl) bicyclo[2.2.2]octan-1- yl)amino)-N-(2-fluoro-3- hydroxy-3-methylbutyl) nicotinamide::US10336762, Compound 406
SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1NC12CCC(CC1)(CC2)C(=O)NC1CC1)-c1ccc2cc(cnn12)C#N
InChI Key InChIKey=BWTHDKOAHNXWOR-GXUJUKEASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 407464
Affinity DataIC50: 1nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair