BDBM407879 6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-((R)-2- fluoro-3-hydroxy-3- methylbutyl)-4-(((1r,3R)- 3-((2-methoxyacetamido) methyl)cyclobutyl) amino)nicotinamide::US10336762, Compound 823
SMILES COC(=O)NC[C@H]1C[C@@H](C1)Nc1cc(ncc1C(=O)NC[C@@H](F)C(C)(C)O)-c1ccc2cc(cnn12)C#N
InChI Key InChIKey=KBLCGJFSDYGQEW-QDOIMOTRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 407879
Affinity DataIC50: <1nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair
Affinity DataEC50: 47nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair