BDBM407888 6-(3-cyanopyrrolo[1,2-b] pyridazin-7-yl)-N-((R)-2- fluoro-3-hydroxy-3- methylbutyl)-4-(((5R,8r)- 2-oxo-1-azaspiro[4.5] decan-8-yl)amino) nicotinamide::US10336762, Compound 832
SMILES CC(C)(O)[C@H](F)CNC(=O)c1cnc(cc1NC1CCC2(CCC(=O)N2)CC1)-c1ccc2cc(cnn12)C#N
InChI Key InChIKey=MNEGHGYMZCFNSO-PXZOHXJQSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 407888
Affinity DataIC50: 1nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair
Affinity DataEC50: 132nMAssay Description:Cryopreserved human monocytes (Stem Cell Technologies) were thawed, diluted in RPMI with GlutaMAX (GibcoŽ 200 mM L-alanyl-L-glutamine) (10 mM HEPES, ...More data for this Ligand-Target Pair