BDBM409271 1-(Cyclobutylmethyl)-6-(4-fluoro-3-methyl-phenyl)pyrrolo[3,2-::US10377753, Example 173
SMILES Cc1cc(ccc1F)-c1cnc2ccn(CC3CCC3)c2c1
InChI Key InChIKey=MTXPFYDPXWYSJL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 409271
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]dofetilide from recombinant human ERG expressed in HEK293 cell membranes measured after 80 mins by TopCount scintillation analysi...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Janssen Research & Development
Curated by ChEMBL
Janssen Research & Development
Curated by ChEMBL
Affinity DataIC50: 402nMAssay Description:Negative allosteric modulation of recombinant human GluN1a/GluN2B expressed in CHO-T-REx cells assessed as inhibition of glutamate/glycine-induced re...More data for this Ligand-Target Pair
Affinity DataIC50: 63.1nMAssay Description:The assay depends on the binding of a tracer to the GluN2B subunit-containing NMDA receptors and the ability of the test compounds to displace such b...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair