BDBM409833 US10370333, Example IV-1::US10370333, Example IV-16::US10370333, Example IV-17

SMILES COC(=O)c1cncc(NS(=O)(=O)c2cc(Br)ccc2OC)c1

InChI Key InChIKey=DKHQHDKBZJGFPZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 409833   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409833(US10370333, Example IV-1 | US10370333, Example IV-...)
Affinity DataIC50: <100nMAssay Description:To determine the inhibition selectivity for inhibitor candidates, human TNAP, PLAP or IAP were added to microtiter plates followed by addition of the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409833(US10370333, Example IV-1 | US10370333, Example IV-...)
Affinity DataIC50: <100nMAssay Description:To determine the inhibition selectivity for inhibitor candidates, human TNAP, PLAP or IAP were added to microtiter plates followed by addition of the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Sanford-Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM409833(US10370333, Example IV-1 | US10370333, Example IV-...)
Affinity DataIC50: <100nMAssay Description:To determine the inhibition selectivity for inhibitor candidates, human TNAP, PLAP or IAP were added to microtiter plates followed by addition of the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent