BDBM410113 US10370370, Compound 9-P2

SMILES Clc1ccc2c(N[C@@H]3CN4CCC3CC4)noc2c1Cl

InChI Key InChIKey=DFGJMJURTZFUDF-LLVKDONJSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 410113   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Axovant Sciences

US Patent
LigandPNGBDBM410113(US10370370, Compound 9-P2)
Affinity DataKi:  26nMAssay Description:α7 nAChR: The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Axovant Sciences

US Patent
LigandPNGBDBM410113(US10370370, Compound 9-P2)
Affinity DataKi:  290nMAssay Description:h-5HT3: In brief, Chinese Hamster Ovary (CHO) cells stably expressing human 5-HT3 serotonin receptors, grown to confluence in 175 cm2 flasks. Followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent