BDBM411160 N-(2,2-Difluoro-ethyl)-N-(2-methoxy-[3,4′]bipyridinyl-3′-yl)-2,6-bis-trifluoromethyl-isonicotinamide::US10385022, Example 156

SMILES COc1ncccc1-c1ccncc1N(CC(F)F)C(=O)c1cc(nc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=RSYPRGMZDDRTQJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411160   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM411160(N-(2,2-Difluoro-ethyl)-N-(2-methoxy-[3,4′]bi...)
Affinity DataEC50:  36nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent