BDBM411189 N-Methyl-3-(2-oxo-pyrrolidin-1-yl)-N-(4-o-tolyl-pyridin-3-yl)-5-trifluoromethyl-benzamide::US10385022, Example 185

SMILES CN(C(=O)c1cc(cc(c1)C(F)(F)F)N1CCCC1=O)c1cnccc1-c1ccccc1C

InChI Key InChIKey=LJRCRGRKZLNVBJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411189   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM411189(N-Methyl-3-(2-oxo-pyrrolidin-1-yl)-N-(4-o-tolyl-py...)
Affinity DataEC50:  2.41E+3nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent