BDBM411196 N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-(2-methanesulfonyl-ethyl)-3,5-bis-tri fluoro methyl-benzamide::US10385022, Example 192

SMILES COc1cc(F)ccc1-c1ccncc1N(CCS(C)(=O)=O)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=ZRKCRXRXXMWCAS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411196   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM411196(N-[4-(4-Fluoro-2-methoxy-phenyl)-pyridin-3-yl]-N-(...)
Affinity DataEC50:  105nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent