BDBM411201 N-Carbamoylmethyl-N-[4-(2-fluoro-phenyl)-pyridin-3-yl]-2,6-bis-trifluoromethyl-isonicotinamide::US10385022, Example 197

SMILES NC(=O)CN(C(=O)c1cc(nc(c1)C(F)(F)F)C(F)(F)F)c1cnccc1-c1ccccc1F

InChI Key InChIKey=DWMLPBHACGYMNB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 411201   

TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM411201(N-Carbamoylmethyl-N-[4-(2-fluoro-phenyl)-pyridin-3...)
Affinity DataEC50:  105nMAssay Description:CHO-dhfr(minus) cells expressing human GPBAR1 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent