BDBM412446 5-cyano-N-(5-(5-ethyl-2-(5- methylisoxazol-3-yl)thiazol-4- yl)pyridin-2-yl)-4- methylnicotinamide::US10399967, Compound 76

SMILES CCc1sc(nc1-c1ccc(NC(=O)c2cncc(C#N)c2C)nc1)-c1cc(C)on1

InChI Key InChIKey=WNSLOPPIXVIMJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412446   

TargetInterleukin-2(Homo sapiens (Human))
Prcl Research

US Patent
LigandPNGBDBM412446(5-cyano-N-(5-(5-ethyl-2-(5- methylisoxazol-3-yl)th...)
Affinity DataIC50:  13nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent