BDBM412451 5-bromo-N-(5-(2-chloro-5- cyclopropoxyphenyl)pyrazin-2-yl)-4- methylnicotinamide::US10399967, Compound 81

SMILES Cc1c(Br)cncc1C(=O)Nc1cnc(cn1)-c1cc(OC2CC2)ccc1Cl

InChI Key InChIKey=PRNVRFDVJHPQFQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412451   

TargetInterleukin-2(Homo sapiens (Human))
Prcl Research

US Patent
LigandPNGBDBM412451(5-bromo-N-(5-(2-chloro-5- cyclopropoxyphenyl)pyraz...)
Affinity DataIC50:  11nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent