BDBM412479 N-(5-(5-ethyl-2-(isoxazol-3- yl)thiazol-4-yl)pyridin-2-yl)-5-fluoro- 4-methylnicotinamide::US10399967, Compound 112

SMILES CCc1sc(nc1-c1ccc(NC(=O)c2cncc(F)c2C)nc1)-c1ccon1

InChI Key InChIKey=PRFOJIMWSJYGKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 412479   

TargetInterleukin-2(Homo sapiens (Human))
Prcl Research

US Patent
LigandPNGBDBM412479(N-(5-(5-ethyl-2-(isoxazol-3- yl)thiazol-4-yl)pyrid...)
Affinity DataIC50:  10nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent