BDBM414040 N-{1-[(7R)-6-{6-chloro- 1H-pyrrolo[2,3-b]pyridin- 4-yl}-7-methyl- 5H,6H,7H,8H-pyrido [4,3-d]pyrimidin-4- yl]piperidin-4- yl}methanesulfonamide::US10421765, Example 29::US10745420, Example 29
SMILES C[C@@H]1Cc2ncnc(N3CCC(CC3)NS(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 414040
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 120nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 120nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair