BDBM414041 2-{1-[(7R)-6-{6-chloro- 1H-pyrrolo[2,3-b]pyridin- 4-yl}-7-methyl- 5H,6H,7H,8H-pyrido[4,3- d]pyrimidin-4-yl]- piperidin-4-yl}propan- 2-ol::US10421765, Example 30::US10745420, Example 30

SMILES C[C@@H]1Cc2ncnc(N3CCC(CC3)C(C)(C)O)c2CN1c1cc(Cl)nc2[nH]ccc12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414041   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM414041(2-{1-[(7R)-6-{6-chloro- 1H-pyrrolo[2,3-b]pyridin- ...)
Affinity DataIC50:  329nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM414041(2-{1-[(7R)-6-{6-chloro- 1H-pyrrolo[2,3-b]pyridin- ...)
Affinity DataIC50:  329nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent