BDBM414085 N-((S)-1-((R)-6-(6- chloro-1H-pyrrolo[2,3-b]- pyridin-4-yl)-7-methyl- 5,6,7,8-tetrahydropyrido- [4,3-d]pyrimidin-4-yl)- piperidin-3-yl)- methanesulfonamide::US10421765, Example 71::US10745420, Example 71
SMILES C[C@@H]1Cc2ncnc(N3CCC[C@@H](C3)NS(C)(=O)=O)c2CN1c1cc(Cl)nc2[nH]ccc12
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 414085
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 73nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 73nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair