BDBM414099 (R)-N-(1-(7-methyl-6- (1H-pyrrolo[2,3-b]- pyridin-4-yl)-5,6,7,8- tetrahydropyrido[4,3-d]- pyrimidin-4-yl)azetidin- 3-yl)cyclopropane- sulfonamide::US10421765, Example 85::US10745420, Example 85
SMILES C[C@@H]1Cc2ncnc(N3CC(C3)NS(=O)(=O)C3CC3)c2CN1c1ccnc2[nH]ccc12
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 414099
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 113nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 113nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair