BDBM414827 (6R,6aS,11aR)-14-(cyclopropyl-methyl)- 2,6a-dihydroxy-5,6,6a,7,10a,11- hexahydro-6,11a-(epiminoethano)- naphtho[2,1-f]indol-9(10H)-one::US10435406, Compound 9

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]4(CC5NC(=O)C=C5C[C@@]34O)c2c1

InChI Key InChIKey=QWRADQWJIXGZKU-CQJNBMRNSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 414827   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM414827((6R,6aS,11aR)-14-(cyclopropyl-methyl)- 2,6a-dihydr...)
Affinity DataKi:  2.16nMAssay Description:Membranes from recombinantHEK-293 cells, CHO or U-2 OS cells expressing the recombinant human κ opioid receptor (κ) were prepared by lysing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM414827((6R,6aS,11aR)-14-(cyclopropyl-methyl)- 2,6a-dihydr...)
Affinity DataKi:  2.34nMAssay Description:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg mem...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent