BDBM4168 1,6-naphthyridin-2(1H)-one deriv. 7a::7-Amino-3-(2,6-dichlorophenyl)-1-methyl-1,6-naphthyridin-2(1H)-one::7-amino-3-(2,6-dichlorophenyl)-1-methyl-1,2-dihydro-1,6-naphthyridin-2-one

SMILES Cn1c2cc(N)ncc2cc(-c2c(Cl)cccc2Cl)c1=O

InChI Key InChIKey=DFQSOVLJNOFZAK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4168   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4168(1,6-naphthyridin-2(1H)-one deriv. 7a | 7-Amino-3-(...)
Affinity DataIC50:  3.60E+3nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4168(1,6-naphthyridin-2(1H)-one deriv. 7a | 7-Amino-3-(...)
Affinity DataIC50:  350nMpH: 7.5 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of Auckland

LigandPNGBDBM4168(1,6-naphthyridin-2(1H)-one deriv. 7a | 7-Amino-3-(...)
Affinity DataIC50:  380nMpH: 7.0 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed