BDBM418603 3-methoxy-4-{[4-{[3- (methylsulfonyl)benzyl]amino}-5- (trifluoromethyl)pyrimidin-2- yl]amino}benzamide (47)::US10450297, Example 47

SMILES COc1cc(ccc1Nc1ncc(c(NCc2cccc(c2)S(C)(=O)=O)n1)C(F)(F)F)C(N)=O

InChI Key InChIKey=DJLXVWDYWBDQSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418603   

TargetFocal adhesion kinase 1 [410-689](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM418603(3-methoxy-4-{[4-{[3- (methylsulfonyl)benzyl]amino}...)
Affinity DataIC50:  0.590nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent