BDBM418607 N-[3-({[2-anilino-5- (trifluoromethyl)pyrimidin-4- yl]amino}methyl)-6-methylpyridin-2-yl]- N-methylmethanesulfonamide (51)::US10450297, Example 51

SMILES CN(c1nc(C)ccc1CNc1nc(Nc2ccccc2)ncc1C(F)(F)F)S(C)(=O)=O

InChI Key InChIKey=IXTUJCPHTJJJDM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418607   

TargetFocal adhesion kinase 1 [410-689](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM418607(N-[3-({[2-anilino-5- (trifluoromethyl)pyrimidin-4-...)
Affinity DataIC50:  0.590nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent