BDBM418652 4-{[4-({3- [methyl(methylsulfonyl)amino]benzyl} amino)-5-(trifluoromethyl)pyrimidin-2- yl]amino}benzamide (99)::US10450297, Example 99

SMILES CN(c1cccc(CNc2nc(Nc3ccc(cc3)C(N)=O)ncc2C(F)(F)F)c1)S(C)(=O)=O

InChI Key InChIKey=LJCRXBCIHWKHHG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418652   

TargetFocal adhesion kinase 1 [410-689](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM418652(4-{[4-({3- [methyl(methylsulfonyl)amino]benzyl} am...)
Affinity DataIC50:  0.380nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent