BDBM418653 N-methyl-4-{[4-({3- [methyl(methylsulfonyl)amino]benzyl} amino)-5-(trifluoromethyl)pyrimidin-2- yl]amino}benzamide (101)::US10450297, Example 101

SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3cccc(c3)N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1

InChI Key InChIKey=FJPBYXZWDNTGTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418653   

TargetFocal adhesion kinase 1 [410-689](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM418653(N-methyl-4-{[4-({3- [methyl(methylsulfonyl)amino]b...)
Affinity DataIC50:  0.590nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent