BDBM418655 N-methyl-4-({4-[({6-methyl-4- [methyl(methylsulfonyl)amino]pyridin- 3-yl}methyl)amino]-5- (trifluoromethyl)pyrimidin-2- yl}amino)benzamide (103)::US10450297, Example 103

SMILES CNC(=O)c1ccc(Nc2ncc(c(NCc3cnc(C)cc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1

InChI Key InChIKey=POLNQAAPWOBRFY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418655   

TargetFocal adhesion kinase 1 [410-689](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM418655(N-methyl-4-({4-[({6-methyl-4- [methyl(methylsulfon...)
Affinity DataIC50:  0.590nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent