BDBM419257 N-isopropyl-N-(4-methoxy- 2-methylphenyl)-3-(S- methylsulfonimidoyl)-4- ((tetrahydro-2H-pyran-4- yl)methoxy)benzene- sulfonamide::US10457637, Compound 143

SMILES COc1ccc(N(C(C)C)S(=O)(=O)c2ccc(OCC3CCOCC3)c(c2)S(C)(=N)=O)c(C)c1

InChI Key InChIKey=QCNYOMWEVRZCBH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419257   

TargetInterleukin-17A(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM419257(N-isopropyl-N-(4-methoxy- 2-methylphenyl)-3-(S- me...)
Affinity DataIC50:  550nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM419257(N-isopropyl-N-(4-methoxy- 2-methylphenyl)-3-(S- me...)
Affinity DataIC50:  550nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent