BDBM419282 (3R)-1-{5-tert-Butyl-3-[(4-methyl-1,2,5-oxadiazol-3-yl)methyl]-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl}pyrrolidine-3-thiol or enantiomer::US10457685, Example 11

SMILES Cc1nonc1Cn1nnc2c(nc(nc12)C(C)(C)C)N1CC[C@@H](S)C1

InChI Key InChIKey=WYVPJXGFSNXEKR-SNVBAGLBSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419282   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM419282((3R)-1-{5-tert-Butyl-3-[(4-methyl-1,2,5-oxadiazol-...)
Affinity DataKi:  640nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCannabinoid receptor 1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM419282((3R)-1-{5-tert-Butyl-3-[(4-methyl-1,2,5-oxadiazol-...)
Affinity DataKi:  8.00E+3nMAssay Description:he affinity of the compounds of the invention for cannabinoid receptors was determined using recommended amounts of membrane preparations (PerkinElme...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent