BDBM419820 US10464919, Example 158

SMILES O=c1[nH]c2cc(CN3C4CCC3CN(C4)c3cnccn3)ccc2c2NCCCc12

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 419820   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419820(US10464919, Example 158)
Affinity DataIC50:  8.23nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419820(US10464919, Example 158)
Affinity DataIC50:  6.59nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TNK1(Homo sapiens (Human))
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419820(US10464919, Example 158)
Affinity DataIC50:  17.3nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent