BDBM419844 US10464919, Example 182

SMILES Fc1cc(CN2CCN(CC2)c2ccc(nn2)C#N)cc2[nH]c(=O)c3CCCNc3c12

InChI Key InChIKey=JQJGYBASPJXNIJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 419844   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419844(US10464919, Example 182)
Affinity DataIC50:  4.02nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419844(US10464919, Example 182)
Affinity DataIC50:  1.26nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TNK1(Homo sapiens (Human))
Je Il Pharmaceutical

US Patent
LigandPNGBDBM419844(US10464919, Example 182)
Affinity DataIC50:  3.33nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent