BDBM419877 US10464927, Compound I-25
SMILES CC(C)n1c(cc2nc(ccc12)-c1nc(Nc2ccc(cn2)N2CCNCC2)ncc1F)C(=O)N(C)C
InChI Key InChIKey=DKAPHJSCSNQZJL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 419877
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Shanghai Xunhe Pharmaceutical Technology
US Patent
Shanghai Xunhe Pharmaceutical Technology
US Patent
Affinity DataIC50: <20nMAssay Description:CDK6: The test compound was dissolved in DMSO and diluted with a kinase buffer solution (20 mM HEPES-pH 7.5, 0.01% Triton X-100, 10 mM MgCl2, 2 mM D...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Shanghai Xunhe Pharmaceutical Technology
US Patent
Shanghai Xunhe Pharmaceutical Technology
US Patent
Affinity DataIC50: <20nMAssay Description:CDK4: The test compound was dissolved in DMSO and diluted with a kinase buffer solution (20 mM HEPES-pH 7.5, 0.01% Triton X-100, 10 mM MgCl2, 2 mM DT...More data for this Ligand-Target Pair