BDBM422046 US10508102, Compound A

SMILES Fc1ccc2cc[nH]c2c1Cl

InChI Key InChIKey=NWWMTPOETWQYKK-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 422046   

TargetTumor necrosis factor(Homo sapiens (Human))
President and Fellows of Harvard College

US Patent
LigandPNGBDBM422046(US10508102, Compound A)
Affinity DataEC50:  90.5nMAssay Description:Compound (Ia) was prepared according to the general methods described above. Compound (Ia) and compound A (below) were screened for anti-necrotic act...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
President and Fellows of Harvard College

US Patent
LigandPNGBDBM422046(US10508102, Compound A)
Affinity DataEC50:  256nMAssay Description:RIP1 kinase assays were performed using ADP-Glo assay (Promega) according to manufacturer's protocol. Reactions were performed in 50 mM HEPES, pH...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTumor necrosis factor(Homo sapiens (Human))
President and Fellows of Harvard College

US Patent
LigandPNGBDBM422046(US10508102, Compound A)
Affinity DataEC50:  324nMAssay Description:Compound (Ia) was prepared according to the general methods described above. Compound (Ia) and compound A (below) were screened for anti-necrotic act...More data for this Ligand-Target Pair
In DepthDetails US Patent