BDBM422140 1-(2,6- dimethoxyphenyl)-5-[4- (6-fluoropyridin-3- yl)benzenesulfonyl]-6- hydroxy-2-[(propan-2- yloxy)methyl]-1,4- dihydropyrimidin-4-one::US10508104, Example 32
SMILES COc1cccc(OC)c1-n1c(O)c(c(=O)nc1COC(C)C)S(=O)(=O)c1ccc(cc1)-c1ccc(F)nc1
InChI Key InChIKey=AXBKZHGIZQTISH-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 422140
Affinity DataEC50: 5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0300nMAssay Description:Agonist activity at mouse APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0200nMAssay Description:Agonist activity at rat APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0100nMAssay Description:Agonist activity at human APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assayMore data for this Ligand-Target Pair