BDBM422192 2-cyclopentyl-5-(4- cyclopropylbenzene- sulfonyl)-1-(2,6- dimethoxyphenyl)-6- hydroxy-1,4- dihydropyrimidin-4-one::US10508104, Example 86
SMILES COc1cccc(OC)c1-n1c(O)c(c(=O)nc1C1CCCC1)S(=O)(=O)c1ccc(cc1)C1CC1
InChI Key InChIKey=HPQYDENIDXYUIF-UHFFFAOYSA-N
Data 4 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 422192
Affinity DataEC50: 5nMAssay Description:HEK293 cells stably expressing human APJ receptor were used to assess the activity of compounds. Cultured cells were detached and resuspended in the ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.400nMAssay Description:Agonist activity at mouse APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at rat APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.300nMAssay Description:Agonist activity at human APJ receptor assessed as effect on cAMP accumulation by cAMP-Glo assayMore data for this Ligand-Target Pair