BDBM423159 5-benzyl-6-(1,5-dimethyl-6-oxo-3-pyridyl)-1-methyl-3,4-dihydroquinolin-2-one::US10501438, Compound 9

SMILES CN1C(=O)CCc2c(Cc3ccccc3)c(ccc12)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=XPYBNGGDEFKYRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 423159   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Neomed Institute

US Patent
LigandPNGBDBM423159(5-benzyl-6-(1,5-dimethyl-6-oxo-3-pyridyl)-1-methyl...)
Affinity DataIC50:  270nMAssay Description:To measure activity of bromodomain inhibitors, a His-epitope tagged BRD4 BD149-170 is purchased from BPS Bioscience. BRD4 binding and inhibition is a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent