BDBM425866 2-(5-chloro-2- hydroxyphenyl)-N-hydroxy- 1H-benzimidazole-6- carboxamide::US10512634, Example 99

SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1cc(Cl)ccc1O

InChI Key InChIKey=UDSJULSJFCELEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425866   

TargetHistone deacetylase 6(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM425866(2-(5-chloro-2- hydroxyphenyl)-N-hydroxy- 1H-benzim...)
Affinity DataIC50:  2nMAssay Description:All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent