BDBM425884 N-hydroxy-2-{4'-[(E)- (hydroxyimino)methyl] biphenyl-4-yl}-1H- benzimidazole-6-carboxamide::US10512634, Example 193

SMILES ONC(=O)c1ccc2nc([nH]c2c1)-c1ccc(cc1)-c1ccc(\C=N\O)cc1

InChI Key InChIKey=JZVHTCIERHZTSM-WSDLNYQXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 425884   

TargetHistone deacetylase 6(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM425884(N-hydroxy-2-{4'-[(E)- (hydroxyimino)methyl] biphen...)
Affinity DataIC50:  11nMAssay Description:All Examples were tested in HDAC1, 2, 3, 6 and 8 in vitro enzymatic assays. The assay principle is well known (Hauser et al. 2009, Bradner et al. 201...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent