BDBM426272 4-[3-(1H-Indazol-5-yl)-4-methyl-2-phenyl-pyrazolo[1,5-c]pyrimidin-7-::US10513523, Example 212

SMILES Cc1cnc(N2CCOCC2)n2nc(c(-c3ccc4[nH]ncc4c3)c12)-c1ccccc1

InChI Key InChIKey=KUTMABJDDSMXNW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426272   

TargetGlutamate receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM426272(4-[3-(1H-Indazol-5-yl)-4-methyl-2-phenyl-pyrazolo[...)
Affinity DataIC50:  0.0800nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent