BDBM426717 4-(8-(3-acrylamidophenyl)quinazolin-6-yl)- N-(4-cyclopropylpyridin-2-yl)benzamide::US10544106, Compound C131::US11208388, Example 131

SMILES C=CC(=O)Nc1cccc(c1)-c1cc(cc2cncnc12)-c1ccc(cc1)C(=O)Nc1cc(ccn1)C1CC1

InChI Key InChIKey=GAWGIOBITJLZNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426717   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Neupharma

US Patent
LigandPNGBDBM426717(4-(8-(3-acrylamidophenyl)quinazolin-6-yl)- N-(4-cy...)
Affinity DataIC50: <100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Neupharma

US Patent
LigandPNGBDBM426717(4-(8-(3-acrylamidophenyl)quinazolin-6-yl)- N-(4-cy...)
Affinity DataIC50: <100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent