BDBM427097 US10544128, Compound 72

SMILES CN1CCC(CC1)c1cccc(c1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn(C)nn1

InChI Key InChIKey=VLIIKCCJFWNHQR-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 427097   

TargetProto-oncogene Wnt-1(Homo sapiens (human))
Samumed

US Patent
LigandPNGBDBM427097(US10544128, Compound 72)
Affinity DataEC50:  62nMAssay Description:The screening assay for Wnt activity is described as follows. Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., col...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM427097(US10544128, Compound 72)
Affinity DataEC50:  5.05E+3nMAssay Description:The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM427097(US10544128, Compound 72)
Affinity DataEC50:  1.90nMAssay Description:The DYRKIA kinase assay was run using the Ser/Thr 18 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Divis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent