BDBM428685 (R or S)-5-[9-ethyl-8-(2- methylpyrimidin-5-yl)-9H- purin-6-yl]-3-(3-methoxy- 3-methylazetidin-1-yl)-3- methyl-1,3-dihydro-2H- indol-2-one::US10544147, Compound 2-1::US10544147, Compound 2-2
SMILES CCn1c(nc2c(ncnc12)-c1ccc2NC(=O)C(C)(N3CC(C)(C3)OC)c2c1)-c1cnc(C)nc1
InChI Key InChIKey=GFTNPBJDAYSSNL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 428685
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 176nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 2nMAssay Description:The PI3-Kinase biochemical assays were developed to measure the intrinsic potency and compound dependent inhibition of the alpha, beta, delta, and ga...More data for this Ligand-Target Pair