BDBM4292 2-(5-hydroxy-1,2,3,4-tetrahydronaphthalen-1-ylidene)propanedinitrile::Tyrphostin deriv. 23

SMILES [#8]-c1cccc2\[#6](-[#6]-[#6]-[#6]-c12)=[#6](/C#N)C#N

InChI Key InChIKey=QTIIRIGGCVGCBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4292   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4292(2-(5-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yliden...)
Affinity DataIC50:  1.20E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed