BDBM429552 (4-Fluoro-2-((S)-3- fluoropyrrolidin-1- yl)phenyl)(1H-imidazol- 2-yl)methanol::US10550089, Example 26::US10995072, Example 26

SMILES OC(c1ncc[nH]1)c1ccc(F)cc1N1CC[C@H](F)C1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 429552   

TargetProteinase-activated receptor 2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM429552((4-Fluoro-2-((S)-3- fluoropyrrolidin-1- yl)phenyl)...)
Affinity DataIC50:  3.87E+3nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProteinase-activated receptor 2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM429552((4-Fluoro-2-((S)-3- fluoropyrrolidin-1- yl)phenyl)...)
Affinity DataIC50:  3.87E+3nMAssay Description:Inositol monophosphate (IP1) production were measured in 1321N1 cells stably expressing human PAR2 using an IP-One HTRF assay kit (Cisbio). 80 nl of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent