BDBM429669 US10550091, No. LC-78::US10947203, No. LC-78

SMILES COc1ccc(Cl)cc1-c1nc(C)c(n1C)S(=O)(=O)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=VGUPCSUIDCCDNR-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 429669   

TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
St. Jude Children''S Research Hospital

US Patent
LigandPNGBDBM429669(US10550091, No. LC-78 | US10947203, No. LC-78)
Affinity DataIC50:  30nMAssay Description:The time-resolved fluorescence resonance transfer (TR-FRET) hPXR competitive binding assay was performed according to the manufacturer's instruct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
St. Jude Children''S Research Hospital

US Patent
LigandPNGBDBM429669(US10550091, No. LC-78 | US10947203, No. LC-78)
Affinity DataIC50:  350nMAssay Description:Displacement of BODIPY FL vindoline from GST-tagged human PXR LBD incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
St. Jude Children''S Research Hospital

US Patent
LigandPNGBDBM429669(US10550091, No. LC-78 | US10947203, No. LC-78)
Affinity DataIC50:  30nMAssay Description:The time-resolved fluorescence resonance transfer (TR-FRET) hPXR competitive binding assay was performed according to the manufacturer's instruct...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent