BDBM430033 US10538528, Compound 15

SMILES COc1cncc(c1)-c1ccc(NCCNC(C)C)c(n1)C1CCN(CC1)c1ncnc2NC(=O)C(C)c12

InChI Key InChIKey=AIZHXUUSVDWSRD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 430033   

TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430033(US10538528, Compound 15)
Affinity DataIC50:  2.10nMAssay Description:Akt1 was prepared and assays of inhibitory activity of the compound according to the present invention against Akt1 kinase activity in vitro were con...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430033(US10538528, Compound 15)
Affinity DataIC50:  0.700nMAssay Description:S6K1: Inhibitory activity of the compound according to the present invention on S6K1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRyanodine receptor 1 [4317-4329]()
Taiho Pahrmaceutical

US Patent
LigandPNGBDBM430033(US10538528, Compound 15)
Affinity DataIC50:  1.10nMAssay Description:Rsk1: Inhibitory activity of the compound according to the present invention on Rsk1 kinase activity in vitro was assayed using the QSS Assist FP ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent